Changing the location or using a mail identity that is located on an external hard disk or a network is not supported. Like Microsoft Entourage for Mac 2008, Outlook 2016 for Mac and Outlook for Mac 2011 are intended to be purely locally cached mail clients. ~/Documents/Microsoft User Data/Office 2011 Identities Outlook for Mac 2011 caches your mail items in an identity in your home folder at the following location: ~/Library/Group Containers/UBF8T346G9.Office/Outlook/Outlook 15 Profiles Outlook 2016 for Mac caches your mail items in a profile in your home folder at the following location: Additionally, using a mail identity or profile that is located on an external hard disk or on a network is not supported in either version of Outlook for Mac. Mac Mail provides only the subset of Outlook features. Secondly, Outlook 2016 for Mac is a complete personal information manager (PIM), whereas Mac Mail is just an email program. Outlook is Personal Information Manager & Mail is Email Client. We do not recommend that you change the default location of your Profile folder for Microsoft Outlook 2016 for Mac, or your Identity folder for Microsoft Outlook for Mac 2011 to an external hard disk or to a network. Because both email clients have their own advantages and disadvantages.
Outlook for Mac is a locally cached email client